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Buhrlage Lab - Cancer Chemical Biology

Sara Buhrlage, PhD
CANCER CHEMICAL BIOLOGY

Lab News

2022
Jun         Congrats to Isabella for passing her qualifying exam and becoming a PhD candidate! 
                  Cara is leaving us to pursue her PhD in Chemistry at Stanford. Best of luck!
               Ujwal Punyamurtula has joined us as a joint lab technician with the Marto Lab. Welcome, Ujwal!


May       Congratulations to Dr. Anthony Varca for successfully defending his thesis! 
              Maria Tarazona Guzman has joined us as a lab technician. Welcome, Maria!
              Cara and Isabella presented posters at the Biological Chemistry and Molecular Pharmacology departmental retreat. 
​

Apr        Wei Pin published a highlight in Molecular Cell titled DUB to the rescue. Check it out!

Mar       The Buhrlage Lab, as part of the Center for Emergent Drug Targets, has received a grant from the Massachusetts Life
              Science Center. Thank you!
             
Congrats to Nick for passing his qualifying exam and becoming a PhD candidate! 
              Anthony A. presented his research at the departmental Data Club! Great job!

Feb        Congrats to Binita for passing her qualifying exam and becoming a PhD candidate!
               Indrajit Sahu has joined us as a joint postdoctoral researcher with the Marto Lab, welcome!
               Nick was awarded the Chleck Family Fellowship! Congrats! 


Jan        Congratulations to Dr. Adrian Chan for successfully defending his thesis! He is moving onto a position in industry, all the
              best!
              Our work on the inhibition of JOSD1 in leukemias with mutant JAK2 was published Leukemia! 


2021
Dec         Congrats to Anthony Varca for publishing his protocol for high-throughput screening for DUB inhibitors in STAR
              Protocols!  

Sept      Congratulations to Sara for earning the title of Associate Professor!      
              
We received an MPN Challenge Grant from the MPN Research Foundation! Thank you for the support!
              Xiaoxi is leaving us for a position in industry! Thank you for all your work building up the foundation of this lab, and all 
              the best in your future endeavors!
             Mona was awarded an NCI-T32 Fellowship. Congrats!

Aug       Isabella joined our lab! Welcome back, for the second time!
              Alex is leaving us to become a young adult fiction author! Send us copies of your book!!!
              Yanran Lu has joined us as a postdoctoral researcher, welcome!

                 Binita has joined as a joint student with the Fischer lab. Welcome!
              Congrats Adrian for publishing his chemoproteomic methods for covalent drug discovery in Chemical Society Reviews!

Jul         Congratulations to Dr. Laura Doherty for successfully defending her thesis! Laura will soon be moving to a research          
              scientist position at the Broad Institute.
              Wei Pin Teh has joined as a postdoctoral researcher, welcome!
              Nick, a graduate student from the Biological and Biomedical Sciences PhD program, has joined as a joint student with
              the Marto lab! Welcome!

Jun        Our high-throughput screen in collaboration with the FAST lab at the Novartis Institutes for BioMedical Research is 
              published in Cell Chemical Biology! Congratulations to Anthony Varca!
              Our review article on using selective inhibitors to investigate DUB biological function is published in Cell Chemical
              Biology! Congratulations Rob!

May      Rob is leaving us for an Associate Scientific Director position at The Mark Foundation for Cancer Research! All the best,
              and we look forward to working together in your new capacity.

Apr      Mona Sharafi has joined as a postdoctoral researcher, welcome!
             Anthony A. was awarded an NIH F31 grant. Congrats!

            Binita, a graduate student from the Biological and Biomedical Sciences PhD program, has started rotating. Welcome!

Mar     Isabella is back as a rotating graduate student in the Chemical Biology PhD program. Welcome back!


Jan        We received funding from the AACR and MPM Transformative Cancer Research Grants Program, thank you for your         
              support!
              Emma, a graduate student in the Chemical Biology PhD program, has started rotating. Welcome!


2020
Oct       Our collaborative study with the Fischer Lab titled "Proteomics-based identification of DUB substrates using selective 
             inhibitors" is out on Cell Chemical Biology. Check it out!
              Jing is leaving us for a PI position at the Hefei Institutes of Physical Science at the Chinese Academy of Sciences! We will
             miss you!

             Zhenze, a joint postdoctoral fellow with the Marto Lab, has joined our lab. Welcome! 

Sept     Our project on USP7 inhibitors for Ewing sarcoma has been selected for a Drug Discovery Partnership from the Mark         
             Foundation for Cancer Research! Thank you for the support!

Aug      Ariana has joined the Buhrlage Lab! Welcome!

Jun       Our R21, co-submitted with Dr. Jarrod Marto, has been funded by the NIH! Thank you for the support!

Mar      Ariana, a graduate student in the Chemical Biology PhD program, has started rotating. Welcome!

Feb       Anthony A., a graduate student in the Chemistry and Chemical Biology PhD Program, has joined our lab. Welcome!
             Bin is leaving us for a scientist position in Delaware. Good luck!


2019
Dec        Our funding from the Ellison Foundation has been renewed. Thank you for the continued support!

Sept       Zack, a graduate student in the Chemistry and Chemical Biology PhD Program, has started rotating. Welcome!

Aug        Xiaoxi has been promoted to Staff Scientist! Congratulations Xiaoxi!
               Rebekka is leaving us to study medicine at the Geothe University Frankfurt in Germany! All the best!
               Cara Starnbach has joined us as a lab technician. Welcome Cara!

Jun         Our R01, co-submitted with Dr. Jarrod Marto, has been funded by the NIH! Thank you for the support!
               Isabella Jaen Maisonet and Ethan DaSilva have joined the lab as summer students! Mathiu is back with us for another                     summer! Welcome (back)!


May       Congratulations to Dr. Nathan Schauer for successfully defending his dissertation!

Jan         We received an ASPIRE Award from the Mark Foundation for Cancer Research! Thank you for the support!


2018
Dec        Alex has joined the Buhrlage Lab! Welcome!
               Our funding from the Ellison foundation has been renewed! Thanks for the continued support!               
 

Nov        Bin Hu, a synthetic chemistry post-doc, has joined the lab. Welcome Bin!
               Alex, a graduate student in the Chemistry and Chemical Biology PhD Program, has started rotating. Welcome!

Oct        Drew, a graduate student in the Chemical Biology PhD Program, has started rotating. Welcome! 

Jun         Exciting news! We received funding from the Gabrielle’s Angel Foundation for Cancer Research!
               Personnel news! Adrian has joined the lab as a joint student with the Marto Lab! Welcome!

Jan         Rebekka has joined the lab as a research technician! Welcome Rebekka!


2017
Dec        Our funding from the Ellison foundation has been renewed! Thanks for the continued support!

Oct         We received funding from the MPN Research Foundation! Thanks for the support!

Sept       Good news! Our grant from the Leukemia and Lymphoma Society has been renewed. Thank you!
               Adrian, a graduate student in the Chemical Biology PhD Program has started rotating. Welcome!

Jul           We received funding from the Claudia Adams Barr Program in Innovative Basic Cancer Research at the DFCI! Thank you!
               Anthony has joined the lab as a graduate student. Welcome!

2016
Dec        Our R01 on USP7 has been funded! Thank you NIH!
               Our funding from the Ellison foundation has been renewed! Thanks for the continued support!

Jul           More good funding news!  We received a DFCI-NU Joint Program Award!  Thank you for the support DFCI and NU!!

Jun         Good news!  We received a LLS New Ideas Award.  Thank you LLS!!
               Welcome Tatiana Mikhailova!!  She is joining us for the summer from Berea College.
               Laura Doherty, a graduate student in the Chemical Biology Ph.D. program, has joined our lab.  Welcome!!

Mar        Laura Doherty received an NSF Graduate Student Fellowship.  Congratulations and great job!!

Feb        Congratulations to Sara and her husband Chris on the birth of Elise Liu!! 

Jan         Moving day!!  The new lab space is gorgeous!  Thank you Gray lab and Structure Core for sharing your space with us for                   the past several months.
               Xiaoxi Liu, a synthetic chemistry post-doc, has joined the lab.  Very excited to get going on chemistry!!
 
2015
Dec        Good news!  We received funding from the Ellison Foundation!  Thank you Ellison Foundation!    

Nov        The lab is growing.  Welcome Jing Yang!

Oct         A warm welcome to Ilaria Lamberto, the first post-doc to join the lab!

Sept       Good news!  We received a Dana-Farber Accelerator grant.  Thank you ORTV for the support!
               Laura Doherty, a graduate student in the Harvard Chemical Biology Ph.D. program, is rotating.  Welcome!! 

Jul           Nathan Schauer, a graduate student in the Harvard Chemical Biology Ph.D. program, has joined the lab.  Welcome!!

Jun         More good funding news!  We received a Dana-Farber Barr grant.

May       Good news! We received a Dana-Farber Medical Oncology Translation grant.     
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